NewsHealth FDA crackdown on poppers prompts rush on popular gay party drug After the FDA raided a popular brand, many fear the Trump administration is ending an era of tolerance.Share this: Click to share on Facebook (Opens in new window) Facebook Click to share on X (Opens in new window) X Click to print (Opens in new window) Print The active ingredient in Rush and other poppers is alkyl nitrite, a chemical that instantly dilates blood vessels when inhaled, producing a brief but intense feeling of euphoria. (Esben Hansen/Dreamstime/TNS) By Tribune News Service | Tribune News ServiceUPDATED: March 21, 2025 at 2:48 PM PDTThere's a rush on Rush. Subscribe to continue reading this article. Already subscribed? To log in, click here. Originally Published: March 21, 2025 at 2:30 PM PDTShare this: Click to share on Facebook (Opens in new window) Facebook Click to share on X (Opens in new window) X Click to print (Opens in new window) Print RevContent Feed